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Publications at JNU
​Aryan Gautam and Pijus K. Sasmal*, "Eradication of Antibiotic-Resistant Gram-Positive Bacteria and Biofilms by Rationally Designed AIE-Active Iridium(III) Complexes Derived from Cyclometalating 2-Phenylquinoline and Ancillary Bipyridyl Ligands"
Inorg. Chem. 2025, 64, 2905-2918. https://doi.org/10.1021/acs.inorgchem.4c05064
Ajay Gupta,† Tarun Adarsh,† Vikas Manchanda, Pijus K. Sasmal* and Shalini Gupta*, "COVID-19 Detection Using AIE-Active Iridium Complexes"
Dalton Trans. 2023, 52, 1188-1192. https://doi.org/10.1039/D2DT03554E
Geeta Kumari,†Ajay Gupta,†Raj Kumar Sah, Aryan Gautam, Monika Saini, Aashima Gupta, Akhilesh K. Kushawaha, Shailja Singh*, and Pijus K. Sasmal*, "Development of Mitochondria Targeting AIE-Active Cyclometalated Iridium Complexes as Potent Antimalarial Agents"
Adv. Healthcare Mater. 2022, 2202411. https://doi.org/10.1002/adhm.202202411
Aakanksha Agarwal, Arun Kumar, Piyush Garg, Arnab Chakraborty, Ranjan Verma, Maryam Sarwat, Ajay Gupta, Pijus K. Sasmal, Yogesh Kumar Verma, Chiranjit Chowdhury, and Monalisa Mukherjee*,
"Algal Biomass-Loaded Hydrogel Scaffolds as a Biomimetic Platform with Antibacterial and Wound Healing Activities"
ACS Appl. Polym. Mater. 2022, 8, 5800–5812.
Ajay Gupta, Aryan Gautam, and Pijus K. Sasmal*, "Photoactivatable o-Hydroxycinnamic Platforms for Bioimaging and Therapeutic Release"
J. Med. Chem. 2022, 65, 5274–5287. https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00022
Neelu Singh,† Ajay Gupta,† Puja Prasad, Raj Kumar Sah, Arvind Singh, Sunil Kumar, Shailja Singh, Shalini Gupta, and Pijus K. Sasmal*, "Mitochondria-Targeted Photoactivatable Real-Time Monitoring of a Controlled Drug Delivery Platform"
J. Med. Chem. 2021, 64, 17813–17823. https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00956
Neelu Singh,† Ajay Gupta,† Puja Prasad, Pritam Mahawar, Shalini Gupta, and Pijus K. Sasmal*, "Iridium-Triggered Allylcarbamate Uncaging in Living Cells"
Inorg. Chem. 2021, 60, 12644–12650. https://pubs.acs.org/doi/abs/10.1021/acs.inorgchem.1c01790
Selected for Featured Article and ACS Editor’s Choice
Puja Prasad, Ajay Gupta, and Pijus K. Sasmal*, "Aggregation-Induced Emission Active Metal Complexes: A Promising Strategy to Tackle Bacterial Infections"
Chem. Commun. 2021, 57, 174–186. https://pubs.rsc.org/en/content/articlelanding/2021/cc/d0cc06037b
Selected for Feature Article and the Journal Cover Page
Ajay Gupta,† Puja Prasad,† Shalini Gupta, and Pijus K. Sasmal*, "Simultaneous Ultrasensitive Detection and Elimination of Drug-Resistant Bacteria by Cyclometalated Iridium(III) Complexes"
ACS Appl. Mater. Interfaces 2020, 12, 35967–35976.
Publications from Ph.D. and Postdoctoral Works
Pijus K. Sasmal,† Shreyas Saha,† and Ki-Bum Lee*, "Photo-triggerable Hydrogel-Nanoparticle Hybrid Scaffolds for Remotely Controlled Drug Delivery"
J. Mater. Chem. B 2014, 2, 7685–7693. https://pubs.rsc.org/en/content/articlelanding/2014/tb/c4tb01436g
Shreyas Saha, Aniruddh Solanki, Pijus K. Sasmal, and Ki-Bum Lee*, "Single Vehicular Delivery of siRNA and Small Molecules to Control Stem Cell Differentiation"
J. Am. Chem. Soc. 2013, 135, 15682–15685. https://pubs.acs.org/doi/10.1021/ja4071738
Puja Prasad, Imran Khan, Pijus K. Sasmal, Debasis Koley, Paturu Kondaiah*, and Akhil R. Chakravarty*, "Planar Triazinium Cations from Vanadyl-mediated Ring Cyclizations: The Thiazole Species for Efficient Nuclear Staining and Photocytotoxicity"
Dalton Trans. 2013, 42, 4436–4449. https://pubs.rsc.org/en/content/articlelanding/2013/dt/c2dt32810k
Pijus K. Sasmal, Craig N. Streu, and Eric Meggers*, "Metal Complex Catalysis in Living Biological Systems"
Chem. Commun. 2013, 49, 1581–1587. https://pubs.rsc.org/en/content/articlelanding/2013/cc/c2cc37832a
Yonggang Xiang, Chen Fu, Tom Breiding, Pijus K. Sasmal, Haidong Liu, Qi Shen, Klaus Harms, Lilu Zhang, and Eric Meggers*, "Hydrolytically Stable Octahedral Silicon Complexes as Bioactive Scaffolds: Application to the Design of DNA Intercalators"
Chem. Commun. 2012, 48, 7131–7133. https://pubs.rsc.org/en/content/articlelanding/2012/cc/c2cc32506c#!divAbstract
Pijus K. Sasmal, Susana Carregal-Romero, Wolfgang J. Parak, and Eric Meggers*, "Light-Triggered Ruthenium-Catalyzed Allylcarbamate Cleavage in Biological Environments"
Organometallics 2012, 31, 5968–5970. https://pubs.acs.org/doi/10.1021/om3001668
Pijus K. Sasmal, Susana Carregal-Romero, Alice A. Han, Craig N. Streu, Zhijie Lin, Kazuhiko Namikawa, Samantha L. Elliott, Reinhard W. Kçster, Wolfgang J. Parak, and Eric Meggers*, "Catalytic Azide Reduction in Biological Environments"
ChemBioChem 2012, 13, 1116–1120. https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.201100719
Babu Balaji, Bhabatosh Banik, Pijus K. Sasmal, Basudev Maity, Ritankar Majumdar, Rajan R. Dighe, and Akhil R. Chakravarty*, "Ferrocene-Conjugated Oxidovanadium(IV) Complexes as Potent Near-IR Light Photocytotoxic Agents"
Eur. J. Inorg. Chem. 2012, 126–135. https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejic.201100836
Puja Prasad, Pijus K. Sasmal, Imran Khan, Paturu Kondaiah, and Akhil R. Chakravarty*, "Schiff Base Oxovanadium(IV) Complexes of Phenanthroline Bases Showing DNA Photocleavage Activity at Near-IR Light and Photocytotoxicity"
Inorg. Chim. Acta 2011, 372, 79–87. https://www.sciencedirect.com/science/article/abs/pii/S0020169311001186
Puja Prasad, Imran Khan, Pijus K. Sasmal, Debasis Koley, Paturu Kondaiah, and Akhil R. Chakravarty*, "Planar Triazinium Cations from VO2+-Assisted Ring Cyclizations: Remarkably Efficient Thiazole Species for Nuclear Staining, PDT and Anaerobic Photocleavage of DNA"
Chem. Commun. 2011, 47, 3954–3956. https://pubs.rsc.org/en/content/articlelanding/2011/cc/c0cc05386d
Bhabatosh Banik, Pijus K. Sasmal, Sovan Roy, Ritankar Majumdar, Rajan R. Dighe, and Akhil R. Chakravarty*, "Terpyridine Oxovanadium(IV) Complexes of Phenanthroline Bases for Cellular Imaging and Photocytoxicity in HeLa Cells"
Eur. J. Inorg. Chem. 2011, 1425–1435. https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejic.201001097
Puja Prasad, Pijus K. Sasmal, Ritankar Majumdar, Rajan R. Dighe, and Akhil R. Chakravarty*, "Photocytotoxicity and Near-IR Light DNA Cleavage Activity of Oxovanadium(IV) Schiff Base Complexes Having Phenanthroline Bases"
Inorg. Chim. Acta 2010, 363, 2743–2751. https://www.sciencedirect.com/science/article/abs/pii/S0020169310001647
Pijus K. Sasmal, Ritankar Majumdar, Rajan R. Dighe, and Akhil R. Chakravarty*, "Photocytotoxicity and DNA Cleavage Activity of L-arg and L-lys Schiff Base Oxovanadium(IV) Complexes Having Phenanthroline Bases"
Dalton Trans. 2010, 39, 7104–7113. https://pubs.rsc.org/en/content/articlelanding/2010/DT/c001867h
Pijus K. Sasmal, Sounik Saha, Ritankar Majumdar, Swati De, Rajan R. Dighe, and Akhil R. Chakravarty*, "Oxovanadium(IV) Complexes of Phenanthroline Bases: The Dipyridophenazine Complex as a Near-IR Photocytotoxic Agent"
Dalton Trans. 2010, 39, 2147–2158. https://pubs.rsc.org/en/content/articlelanding/2010/DT/b917265c
Pijus K. Sasmal, Sounik Saha, Ritankar Majumdar, Rajan R. Dighe, and Akhil R. Chakravarty*, "Photocytotoxic Oxovanadium(IV) Complexes Showing Light-induced DNA and Protein Cleavage Activity"
Inorg. Chem. 2010, 49, 849–859. https://pubs.acs.org/doi/10.1021/ic900701s
Pijus K. Sasmal, Sounik Saha, Ritankar Majumdar, Rajan R. Dighe, and Akhil R. Chakravarty*, "Oxovanadium(IV)-based Near-IR PDT Agents: Design to Biological Evaluation"
Chem. Commun. 2009, 1703–1705. https://pubs.rsc.org/en/content/articlelanding/2009/cc/b822229k
Pijus K. Sasmal, Ashis K. Patra, and Akhil R. Chakravarty*, "Synthesis, Structure, DNA Binding and DNA Cleavage Activity of Oxovanadium(IV) N-salicylidene-S-methyldithiocarbazate Complexes of Phenanthroline Bases"
J. Inorg. Biochem. 2008, 102, 1463–1472. https://www.sciencedirect.com/science/article/pii/S0162013408000184
Pijus K. Sasmal, Ashis K. Patra, Munirathinam Nethaji, and Akhil R. Chakravarty*, "DNA Cleavage by New Oxovanadium(IV) Complexes of N-salicylidene α-amino Acids and Phenanthroline Bases in the Photodynamic Therapy Window"
Inorg. Chem. 2007, 46, 11112–11121. https://pubs.acs.org/doi/10.1021/ic7011793
Patents
Indian Patent No.: 401771
Application No.: 202011027461
Title: A Multi-Targeted Iridium(III)-Platinum(IV) Conjugates as Potent Anticancer Prodrugs to Overcome Drug Resistant Cancer
Date of Filing: 29/06/2020
Date of Grant: 21/07/2022
​
Indian Patent Application No.: 202111015826
Title: Mitochondria-Targeted Photoactivatable Drug Delivery Platform: A Strategy for Real-Time Monitoring of Controlled Drug Release
Date of Filing: 03/04/2021
​Ajay Gupta, Neelu Singh, Aryan Gautam, Neetesh Dhakar, Sunil Kumar and Pijus K. Sasmal*, "Visible and NIR-Light Photoactivatable o-Hydroxycinnamate System for Efficient Drug Release with Fluorescence Monitoring"
RSC Med. Chem. 2023, 14, 1088-1100. https://doi.org/10.1039/D2MD00438K
​Aryan Gautam, Ajay Gupta, Puja Prasad, and Pijus K. Sasmal*, "AIE-Active Cyclometalated Iridium(III) Complex for Detection of Lipopolysaccharide and Wash-free Imaging of Bacteria"
Dalton Trans. 2023, 52, 7843-7853. https://doi.org/10.1039/D3DT00628J
​Ajay Gupta, Abhishek Kumar Pandey, Titas Mondal, Jaydeep Bhattacharya* and Pijus K. Sasmal*, "Multifuntional Iridium(III)-Platinum(IV) Conjugates as Potent Anticancer Theranostic Agents"
J. Med. Chem. 2023, 66, 8687-8704. https://doi.org/10.1021/acs.jmedchem.3c00336
​Gomathi Sivakumar, Ajay Gupta, Anashwara Babu, Pijus K. Sasmal,* and Samarendra Maji*, "Nitrodopamine Modified MnO2 NS-MoS2QDs Hybrid Nano-composite for Extra- and Intracellular Detection of Glutathione"
J. Mater. Chem. B, 2024, 12, 4724-4735. https://doi.org/10.1039/D3TB03068G
​Deepika Chauhan, Puja Prasad, and Pijus K. Sasmal*, "Organoiridium-Catalyzed Bioorthogonal Chemistry"
Coord. Chem. Rev. 2024, 520, 216139. https://doi.org/10.1016/j.ccr.2024.216139
​Ajay Gupta and Pijus K. Sasmal*, "Multi-Funtional Biotinylated Platinum(IV)-SAHA Conjugate for Tumor-Targeted Chemotherapy"
Dalton Trans. 2024, 53, 17829-17840. https://doi.org/10.1039/D4DT01571A
​Aryan Gautam, Ajay Gupta, Puja Prasad, and Pijus K. Sasmal*, "Development of Cyclometalated Iridium(III) Complexes of 2-Phenylbenzimidazole and Bipyridine Ligands for Selective Elimination of Gram-Positive Bacteria"
Chem. Asian J. 2024, 20, e20241060. https://doi.org/10.1002/asia.202401060
